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This 1 supplement can reverse diabetes symptoms in men
Matt Cook here, and I’m always looking for natural supplements that can benefit men.
And nicotinamide riboside is a supplement which is gaining more and more of my interest.
It’s a substance which helps the body to generate energy more efficiently.
It works in a very similar way to a more common form of vitamin B3 called niacinamide.
Recent articles have been published showing that this supplement could help with Parkinson’s disease, alcoholic liver damage, and numerous metabolic health problems.
And because it improves our energy production, it can play a massive role in metabolic health.
Recent animal experiments have shown that nicotinamide riboside can help with diabetes…
…as well as many of the complications associated with that metabolic disorder.
The research was carried out at Carver College of Medicine, University of Iowa. The findings were published in Nature Research Scientific Reports.
This research was carried out on rodents.
There are 2 ways in which lab animals are given type II diabetes or prediabetes.
One is using a chemical called streptozotocin, the other involves feeding the animals a high-fat diet.
Both methods produce many of the diabetes associated complications – including peripheral neuropathy.
“Mice fed on a high-fat diet become diabetic and develop insulin resistance and neuropathy. Given streptozotocin they develop type II diabetes, hyperglycaemia, severe insulin resistance and neuropathy.”
Nicotinamide riboside has the ability to increase the body’s production of something called NAD+.
NAD + is one of the most essential elements for optimal energy production.
“Because NAD + might address glycaemic control and be neuroprotective, we treated prediabetic and type II diabetic mice with nicotinamide riboside added to a high-fat diet.”
The speculation was correct, there was a whole host of benefits for these animals given nicotinamide riboside.
When prediabetic animals were fed a high-fat diet…
Blood sugar improved.
They gained less weight.
Diabetic liver damage was reduced - including hepatic steatosis.
Neuropathy was reduced or prevented.
“Nicotinamide riboside improves glucose tolerance, reduced weight gain, liver damage and the development of hepatic steatosis in prediabetic mice while protecting against sensory neuropathy.”
The researchers found similar benefits in the other mice.
Those mice were fully diabetic after having been given the toxic chemical streptozotocin.
Researchers discovered nicotinamide riboside…
Reduce blood sugar.
Reduced weight gain.
Reduced liver damage including hepatic steatosis.
Protected against diabetic neuropathy.
“In type II diabetic mice, nicotinamide riboside greatly reduced non-fasting and fasting blood glucose, weight gain and hepatic steatosis while protecting against diabetic neuropathy.”
The researchers were surprised at the extent of the benefits provided by the supplement.
They suspected they might see some benefits due to the fact that nicotinamide riboside is known to help with blood sugar control.
But the extent of the benefits – improving almost every complication of type II diabetes of type II diabetes and prediabetes – was quite a surprise.
“The protective effect of nicotinamide riboside could not be explained by glycaemic control alone.”
The researchers carried out a detailed examination of the cornea of the animals.
The cornea is a structure in the eye which could be considered part of the brain or nervous system.
It’s an easy way to assess the health of the nervous system overall.
Damage to the corneal structure is a very good indicator of neurodegeneration – damage to the brain and central nervous system.
The researchers found a remarkable protective effect from nicotinamide riboside on the corneal structure.
This indicates that the supplement protects against neurodegeneration, brain and central nervous system problems, induced by diabetes.
The researchers also looked for changes in NAD+ and related pro-energetic compounds. (NADP+ and NADPH)
As expected, nicotinamide riboside boosted these energetic compounds which are depleted by diabetes.
“NADP+ and NADPH levels were degraded in diabetes but were largely protected when mice were supplemented with nicotinamide riboside.”
Nicotinamide riboside could have massive benefits for people with diabetes because it helps the body to generate energy more efficiently.
“The data justifies testing of nicotinamide riboside in human models of obesity, type II diabetes and associated neuropathies.”
The supplement works in ways similar to a number of other supplements on the market.
This includes nicotinamide mononucleotide and the less exotic (and less expensive) niacinamide (a form of vitamin B3).
