Daily Shaarli

All links of one day in a single page.

April 13, 2025

This new treatment doubles cardiovascular risks

Matt Cook here, and aspirin is an amazing substance.

It can lower the risk of most common chronic diseases – including colorectal cancer.

One of the things aspirin does is inhibit an enzyme called COX-2.

This has led to studies showing that COX-2 inhibitors can reduce colorectal cancer.

But many other COX-2 inhibitors are not as safe as aspirin…

Studies have shown that using the COX-2 inhibitor celecoxib to reduce colorectal cancer can double your risk of cardiovascular problems.

This treatment is also used for acute pain, ankylosing spondylitis, dysmenorrhea, osteoarthritis, rheumatoid arthritis, and migraines.

The human research was carried out at Brigham and Women's Hospital in Boston. This paper was published in Circulation.

The researchers looked at data from trials on the ability of the COX-2 inhibitor celecoxib to reduce adenomatous polyps.

These are growths in the colon or rectum, usually benign, but they can develop into colorectal cancer over time.

The researchers analyzed data from studies that used different doses of celecoxib or placebo over a long period.

The studies tracked all sorts of health metrics – including serious cardiovascular events.

The researchers found that higher daily doses of celecoxib were associated with greater cardiovascular problems.

Taking 400mg of celecoxib once a day was associated with a 30% increase in cardiovascular issues.

Taking 400mg twice daily was associated with a 240% increase in cardiovascular issues.

Taking this treatment was associated with a near doubling of major cardiovascular risk!

The researchers also found a significant increase in blood pressure in people taking these treatments.

Again, higher doses were associated with a greater increase in blood pressure.

The longer people use these treatments, the greater the increase in blood pressure.

Inhibiting COX-2 very likely decreases the risk of colorectal cancer. It's a good thing to do.

But it's important to pay attention to the method.

While low doses of the COX-2 inhibitor aspirin can be beneficial and safe, other COX-2 inhibitors like celecoxib can have major side effects.

Using this treatment regularly seems to double the risk of major cardiovascular problems.

The treatment also clearly increases blood pressure.

This can cause further problems, as doctors may try to deal with the increase in blood pressure by using other harmful treatments.**

Aspirin is a very useful treatment. But it's out of patent, extremely cheap, and not profitable.

Big Pharma is always trying to replace aspirin with patentable treatment.

But every time they do this, they come up with something that fits a narrow biochemical definition but has disastrous health consequences.

-Matt Cook / malehealthcures.com

Penile Health and Blood Pressure Medications

Matt Cook here, and disease states which are usually reversible lead to the narrowing and tightening of blood vessels.

This changes blood flow – restricting its movement around the body.

Inadequate blood flow starves every part of the body – including the penis.

When blood flow becomes more difficult, the body increases blood pressure to try and force more blood to the muscles and organs.

This is one of the reasons why high blood pressure is associated with poor rockiness.

It’s not blood pressure that causes the problem – blood pressure is just a side-effect.

That’s a topic for another time – I have covered it in detail in my newsletters.

But there is another factor that can cause penis problems…

It seems that the treatments commonly used to treat high blood pressure also cause poor rockiness – or make it worse.

At least some of them do..

The human research was carried out at Wake Forest University School of Medicine. This paper was published in The Journal of Clinical Hypertension.

Rockiness problems and other sexual problems have been linked to both high blood pressure and blood pressure treatments.

This worries doctors and researchers because if these treatments affect your sex life people are less likely to take them.

The optimal solution is to solve the issue causing high blood pressure so you don’t need the treatments…

…not to suppress the symptom with treatments which cause other problems.

This research paper was written to inform doctors about the effects of different blood pressure treatments on sex life…

…so they can recommend treatments that men are more likely to take.

Blood pressure treatments can often cause sexual problems – so changing treatments can solve that issue – at least for a while.

The research involved analyzing a lot of previous studies on different blood pressure treatments.

The authors also looked at lots of reports from men using these treatments.

Numerous studies have shown that men who use blood pressure treatments often report sexual side effects – not good ones.

But some blood pressure treatments seem less harmful to libido and sexual performance.

One blood pressure treatment called losartan actually seemed to improve the sex life of men with high blood pressure.

A number of human studies showed that losartan actually improved rockiness, sexual satisfaction, and frequency of sexual activity in men.

Blood pressure treatments like losartan might actually improve sexual function – quite the opposite of most blood pressure treatments.

Losartan lowers blood pressure by acting on an enzyme called angiotensin II.

This enzyme also affects the ability to get rocky.

Losartan changes how the penis handles blood flow.

You should always work closely with your doctor regarding your treatments.

If you’re having these problems your doctor might be interested in changing your treatments to one which has fewer side effects.

I think the best solution is to reverse the problems causing poor blood flow in the first place…

Because these problems are the root cause of high blood pressure and rockiness problems.

-Matt Cook / malehealthcures.com